By Kursad Turksen (Author)
This entire overview of our present figuring out of grownup stem telephone forms and their rules examines the derivation, characterization, and application of grownup stem cells present in skeletal muscle, dental pulp, prostate, kidney, the attention, internal ear, and different tissues. The authors pay particular awareness to grownup stem phone plasticity and their application in general tissue homeostasis, in addition to their functions in regenerative medication.
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Additional info for Adult Stem Cells
Satellite cells of skeletal muscle coexpress myogenic and endothelial markers, further suggesting that at least some adult stem cells might be derived from vascular lineage. However, the exact identity of these hypothetical blood vessel-based pluripotent precursor cells remains to be established. 5. ADULT SATELLITE CELL SELF-RENEWAL The mechanisms regulating the self-renewal of satellite cells in adult skeletal muscle are still poorly understood. To proliferate, if satellite cells have to activate the expression of MRFs, it is unclear how they return to the quiescent state after the rounds of proliferation and avoid terminal differentiation.
48 d in the human). The Adark spermatogonia are quiescent and only are activated after cell loss. When these cells are activated, they become Apale spermatogonia first and then start to proliferate. During repopulation by surviving stem cells, new Adark spermatogonia are set aside again (55). In comparing primate to nonprimate spermatogenesis, it is clear that there is much less proliferative activity of the stem cells in the primate seminiferous epithelium, even by the active stem cells, the Apale.
1973). The fine morphology of mouse primordial germ cells in extragonadal locations. Am J Anat 137, 299–335. 36 de Rooij Stem Cells in Skeletal Muscle 37 3 Stem Cells in Skeletal Muscle Anna Polesskaya and Michael Rudnicki 1. INTRODUCTION Skeletal muscle is responsible for movement in animals. Pathologies of muscle tissue have serious consequences for the patient, such as decreased mobility, paralysis, and, in extreme cases, death. Often, those conditions are refractory to conventional medical treatments.
Adult Stem Cells by Kursad Turksen (Author)